British researchers from Oxford University said that the widespread synthetic glucocorticosteroid dexamethasone significantly reduces the risk of death for patients who coronavirus infection COVID-19 severe. It is reported by British television and radio BBC.
Study of dexamethasone, according to the publication, are part of global trials of the effectiveness of existing therapies and drugs for the treatment of coronavirus infection.
British scientists say that a small dose of dexamethasone by a third (from 40 to 28%) reduces the risk of death for patients on the ventilator, and one-fifth (from 25 to 20%) for patients receiving oxygen support. The researchers argue that the use of the drug epidemic in great Britain would save up to 5 thousand lives.
Scientists say that dexamethasone is used to reduce inflammation in other diseases and, apparently, helps to prevent the so-called cytokine storm an excessive immune response to the coronavirus. In this case, when a light course of the disease, dexamethasone is probably useless.
Professor Peter Horby, who led the research, called the results obtained breakthrough. He said that at the moment, “it is the only drug that reduces mortality”.
BBC recalls that the dexamethasone used since the beginning of 1960-ies for the treatment of a wide range of diseases, such as rheumatoid arthritis and asthma. Half of all patients with COVID-19 who need artificial ventilation of the lungs do not survive, so the reduction by one third the risk of death for these patients “would have a huge impact,” emphasizes the publication.
Flash coronavirus infection COVID-19 began in late 2019 in China. March 11, 2020, the world health organization declared the spread of the coronavirus pandemic. According to data from the American Johns Hopkins University, the total number of infected people in the world exceeded 8,06 million, more than the 3.89 million recovered, 437 thousand died.