Scientists have captured on video how the brain gets rid of dead neurons

Daily in the human body die tens of billions of cells, which is a natural part of his life. The biodegradable waste will be disposed of, clearing the way for new cells. As this process takes place with the neurons of the brain, for the first time saw researchers from Yale school of medicine (USA).

The scientists used a new system “2Phatal”, which tinted fluorescent dye individual neurons, and then killed them. It all happened on live mice, but to a limited extent, not to disrupt neural activity of animals. The main task is to study, how exactly is recycling dead neurons.

It turned out that all the work is done by three types of glial cells. The first is activated microglia, which absorbs the main body of the neuron, which takes a few hours. In parallel, astrocytes destroy the remnants of dendrites – past relations of the cell to other neurons. Finally, the void is filled NG2 cells. The work of all three components are closely interrelated and when one of them slowing down or inability to continue the whole process slowed down and can even “stand in pause”.

The researchers noticed a decrease in the rate of recycling depending on the age of the body. The older media of neurons, the slower the process. Perhaps this explains why age-related neurodegenerative diseases – the body has no time to get rid of dead neurons, leading to their accumulation. And this leads us to the idea to develop a mechanism to force cleanup of dead brain neurons to help the elderly to the body faster to get rid of them.

Leave a Reply

Your email address will not be published. Required fields are marked *


Physicists have learned to turn plastic bottles in supercapacitors

Scientists from the University of California, riverside have developed a technology to produce components for supercapacitors from regular waste. We are talking about polyethylene terephthalate or PET, which is made most of plastic bottles. This material is from an economic point of view is significantly superior to high-tech raw materials, like graphene or carbon nanotubes. […]

Looks like a screwdriver of the XXI century

Recently Techcult wrote about the drill of the XXI century with a touchscreen and lasers. But the screwdriver is traditionally considered to be more simple, reliable and very straightforward tool. What similar high-tech screwdriver advanced Italian production? And it is similar to the Kinetic device Driver. Kinetic Driver designed by the Italian designer Giacomo Di […]

Our Solar system is most similar to space croissant

The sun emits powerful electromagnetic winds that envelop the planet in our solar system like a giant bubble. This magnetic bubble is called the heliosphere and protects the planet from dangerous space radiation. Scientists have long believed that the heliosphere is in the form of a comet – with a distinct nose and long flowing […]

Some homemade masks turned out to be more dangerous than no

Despite the fact that the industry has recovered from the shock of the first days of the pandemic COVID-19 and now produces enough facial masks of different types, most people in the world due to various reasons use homemade versions. Everyone understands that they are less effective than professional medical model, but the question is: […]