Exploding microbubbles surprisingly effectively destroy cancerous tumors

Engineers from both biomedical doctors from tel Aviv University (Israel) developed a new effective weapon to fight cancer tumors. They learned to destroy their local explosions, using microscopic bubbles of gas. And to enhance the effect, they added to this bioprivacy additional striking element gene immunotherapy.

Initially, the Israeli researchers studied the effect on cancers of the ultrasound, but then turned his attention to the behavior of microbubbles. At irradiation at high frequencies the bubbles are compressed, and at low frequencies – extended. Picking up the right frequency, the scientists have made an explosive expansion effect, which was a tool against cancer cells.

The gas microbubbles are injected directly into the tumor, then turn the ultrasound emitter at frequency of 250 kHz and the microexplosion occurs. Exploding bubbles to destroy up to 80% of the tumor and to eliminate the remaining cells use the gene immunotherapy. It causes cells to produce a signaling substance that attracts phagocytes and “highlights” for them.

The explosion destroys the center of the tumor, punches holes in the membrane and opens the way to attack the immune system, which finishes off the remaining cells. The technology has been successfully tested on models of breast cancer and showed excellent results. Now comes the test – can it help to temporarily penetrate the blood-brain barrier, which prevents the delivery of drugs to the target organs.

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